Skip to main content

Table 1 Baseline characteristics

From: Association between baseline LDL-C and prognosis among patients with coronary artery disease and advanced kidney disease

Characteristica

Missing Data

Overall (N = 803)

LDL-C ≥ 1.8 mmol/L(N = 665)

LDL-C < 1.8 mmol/L(N = 138)

P value

Demographic characteristics

 Age, year

0 (0)

67.4 (10.3)

67.5 (10.2)

66.8 (10.8)

0.44

 Male, n (%)

0 (0)

550 (68.5)

450 (67.7)

100 (72.5)

0.32

Coexisting conditions

 Current smoker, n (%)

0 (0)

117 (14.6)

99 (14.9)

18 (13.0)

0.67

 ACS, n (%)

0 (0)

386 (48.1)

328 (49.3)

58 (42.0)

0.14

 CHF, n (%)

0 (0)

381 (47.4)

312 (46.9)

69 (50.0)

0.57

 Hypertension, n (%)

0 (0)

654 (81.4)

530 (79.7)

124 (89.9)

0.008

 Diabetes mellitus, n (%)

0 (0)

429 (53.4)

343 (51.6)

86 (62.3)

0.03

 Dialysis, n (%)

0 (0)

283 (35.2)

216 (32.5)

67 (48.6)

< 0.001

 Anemia, n (%)

2 (0.2)

662 (82.6)

537 (80.9)

125 (91.2)

0.005

 PAD, n (%)

0 (0)

91 (11.3)

80 (12.0)

11 (8.0)

0.22

eGFR, ml/min/1.73 m2

0 (0)

18.0 (8.3)

18.4 (8.1)

15.9 (8.9)

0.001

  15 ≤ eGFR < 30 ml/min/1.73 m2, n (%)

0 (0)

499 (62.1)

431 (64.8)

68 (49.3)

0.001

Previous AMI, n (%)

0 (0)

64 (8.0)

54 (8.1)

10 (7.2)

0.86

PCI, n (%)

0 (0)

440 (54.8)

365 (54.9)

75 (54.3)

0.98

Laboratory examination

 WBC, 109/L

2 (0.2)

8.6 (3.3)

8.6 (3.3)

8.5 (3.7)

0.67

 ALB, g/L

1 (0.1)

32.7 (5.1)

32.9 (5.2)

32.0 (4.5)

0.06

 Total Cholesterol, mmol/L

1 (0.1)

4.4 (1.3)

4.6 (1.3)

3.2 (0.8)

< 0.001

 LDLC, mmol/L

0 (0)

2.7 (1.0)

2.9 (0.9)

1.5 (0.3)

< 0.001

 TRIG, mmol/L

0 (0)

1.3 (1.36)

2.0 (1.3)

1.8 (1.4)

0.09

 HDLC, mmol/L

0 (0)

0.9 (0.3)

0.9 (0.3)

0.8 (0.2)

< 0.001

 Lg ProBNP, pg/mL

113 (14.1)

3.7 (0.7)

3.7 (0.7)

3.8 (0.7)

0.18

 Lg D-dimer, ng/mL

42 (5.2)

3.1 (0.4)

3.1 (0.4)

3.0 (0.4)

0.71

Medications

 ACEI/ARB, n (%)

0 (0)

329 (41.0)

268 (40.3)

61 (44.2)

0.45

 β-blockers, n (%)

0 (0)

542 (67.5)

453 (68.1)

89 (64.5)

0.47

 Statins, n (%)

0 (0)

717 (89.3)

593 (89.2)

124 (89.9)

0.93

 Diuretics, n (%)

0 (0)

337 (42.0)

281 (42.3)

56 (40.6)

0.79

Events

 Death, n (%)

0 (0)

312 (38.9)

238 (35.8)

74 (53.6)

< 0.001

  1. a Data are presented as the mean value standard deviation or percentage of participants
  2. Abbreviations: LDL-C Low-density lipoprotein cholesterol; ACS Acute coronary syndrome; CHF Congestive heart failure; PAD Peripheral arterial disease; eGFR Estimated glomerular filtration rate; AMI Acute myocardial infarction; PCI Percutaneous coronary intervention; HDL-C High-density lipoprotein cholesterol; TRIG Triglycerides; WBC White blood cell; pro-BNP Pro-brain natriuretic peptide; ACEI Angiotensin-Converting Enzyme Inhibitors; ARB Angiotensin Receptor Blockers