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Table 1 Characteristics of the study sample, the drop outs and the excluded participants

From: Processing speed is affected by early impairment in kidney function in the general elder population

Variable

Participants included in the study classified by eGFR

All participants included in the study

Individuals not included in the study

eGFR unchanged < 60 from baseline to 6 year follow up

eGFR unchanged from >= 60 from baseline to 6 year follow up

 

Excluded due to transition from eGFR <60 to >=60 from baseline to follow up or vice versa

Lost to follow up

Excludeda

Number

196

709

905

128

1099

799

Age (mean)

78.45 (SD 7.95)

64.65 (SD 5.82)

67.64 (SD 8.52)

71.98 (SD 8.15)

78.67 (SD 10.47)

70.29 (SD 9.68)

Sex

 Women

67.9 %

50.8 %

54.5 %

51.6 %

56.4 %

57.2 %

 Men

32.1 %

49.2 %

45.5 %

48.4 %

43.6 %

42.8 %

Education

 ≤ fulfilled elementary school

62.2 %

43.6 %

47.6 %

63.3 %

61.0 %

54.5 %

 fulfilled secondary school

27.0 %

30.3 %

29.6 %

18.8 %

27.1 %

26.9 %

 ≥ year of higher education

10.7 %

26.1 %

22.8 %

18.0 %

11.9 %

18.7 %

Hypertension

44.4 %

18.8 %

24.3 %

31.3 %

37.1 %

25.9 %

Diabetes

11.7 %

5.5 %

6.9 %

9.4 %

10%

5.5 %

Smoking habits

 Active smoker

11.2 %

21.2 %

19.0 %

12.5 %

15.1 %

17.2 %

 Former smoker

34.2 %

40.6 %

39.2 %

44.5 %

37.0 %

36.4 %

 Never smoked

54.6 %

38.2 %

41.8 %

43.0 %

48.0 %

46.4 %

eGFR (mean)

48.44 (SD 9.15)

80.90 (SD 11.48)

73.87 (SD 17.33)

66.28 (SD 8.58)

56.72 (SD 20.34)

70.15 (SD 17.76)

eGFR (median)

50.57

(Q1 43.16, Q3 55.95)

79.52

(Q1 72.24 , Q3 88.82)

76.02

(Q1 62.97, Q3 86.32)

64.76

(Q1 60.57, Q3 70.90)

55.31

(Q1 41.92, Q3 71.03)

71.89

(Q1 57.41, Q3 82.96)

  1. Characteristics of the study sample in the relation to eGFR
  2. eGFR in mL/min/1,73 m2 estimated from creatinine and cystatin C using the CKD-EPI formula
  3. Abbreviations: eGFR estimated glomerular filtration rate, Q quartile, SD standard deviation
  4. aExcluded due to dementia or MCI at baseline, depression, non-participation in cognitive tests, missing data from education, smoking, CRD or missing blood samples