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Table 3 Comparison of blood pressure, renal function, serum albumin, and urine sodium and potassium after treatment with furosemide alone or with the combination of furosemide plus albumin in chronic kidney disease patients

From: The added-up albumin enhances the diuretic effect of furosemide in patients with hypoalbuminemic chronic kidney disease: a randomized controlled study

  Furosemide Furosemide + Albumin P-value
Mean ± SD Mean ± SD  
Blood pressure (mmHg)    
6 hours systolic 132.0 ± 5.1 132.4 ± 6.2 0.60
diastolic 80.1 ± 5.3 80.6 ± 5.3 0.52
24 hours systolic 131.6 ±4.6 132.0 ±5.6 0.60
diastolic 79.7 ± 5.3 80.2 ± 5.5 0.57
Calculated GFR (mL/min/1.732)    
6 hours 27.8 ± 12.6 27.2 ± 10.5 0.64
24 hours 29.1 ± 12.3 28.3 ± 11.3 0.23
Serum albumin (g/dL)    
6 hours 2.98 ± 0.30 3.46 ± 0.42 < 0.01
24 hours 2.97 ± 0.31 3.42 ± 0.41 < 0.01
Urine volume at 6 hours (L) 0.90 ± 0.35 1.07 ± 0.34 0.02
Urine volume at 24 hours (L) 2.44 ± 0.74 2.47 ± 0.60 0.81
Urine sodium at 6 hours (mEq) 54.9 ± 31.6 70.8 ± 31.3 < 0.01
Urine sodium at 24 hours (mEq) 146.8 ± 59.9 154.4 ± 42.2 0.53
Urine potassium at 6 hours (mEq) 14.7 ± 8.0 18.0 ± 8.9 0.03
Urine potassium at 24 hours (mEq) 40.5 ± 10.0 40.3 ± 7.4 0.95
  1. GFR = Glomerular filtration rate SD = standard deviation.