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Table 2 Effect of addition of MRA on final visit blood pressure

From: Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis

Variable

Measurement

No. of study groups

No. patients in intervention

No. patients in placebo/control

Effect size (95 % CI)

I2 (p value)

Systolic BP (mmHg)

Change from baseline

9

260

266

−3.30 (−5.56, −1.04)

40.0 % (0.101)

Final visit

16

666

659

−5.69 (−9.04, −2.34)

81.8 % (0.000)

Diastolic BP (mmHg)

Change from baseline

9

260

266

−2.84 (−3.35, −2.33)

0.0 % (0.799)

Final visit

16

666

659

−1.73 (−3.37, −0.10)

68.3 % (0.000)