Table 4 Univariate and multivariate models analysing the correlations between changes (Δ) in PWV, eGFR, copeptin, cIMT and FMD in ADPKD patients

ΔBMI (kg/m²)

0.056(0.429)

-

−0.053(0.457)

-

0.083(0.243)

-

0.019(0.685)

-

0.133(0.054)

-

ΔCalcium (mg/dl)

0.206(0.003)

-

0.011(0.881)

-

−0.038(0.595)

-

0.134(0.200)

-

0.063(0.420)

-

ΔPhosphorus (mg/dl)

0.113(0.112)

-

0.027(0.708)

-

0.117(0.100)

-

0.109(0.150)

-

0.055(0.460)

-

ΔHDL Cholesterol (mg/dl)

0.117(0.099)

-

−0.149(0.035)

−0.175(0.002)

0.071(0.319)

-

0.085(0.365)

-

−0.048(0.484)

-

ΔLDL Cholesterol (mg/dl)

0.260(<0.001)

-

−0.037(0.604)

-

−0.016(0.827)

-

0.053(0.460)

-

−0.038(0.594)

-

ΔTotal Cholesterol (mg/dl)

−0.111(0.118)

-

−0.143(0.044)

-

0.056(0.432)

-

0.091(0.332)

−0.056(0.360)

-

ΔTriglyceride (mg/dl)

0.170(0.016)

-

0.194(0.006)

0.146 (0.010)

−0.101(0.154)

-

−0.107(0.102)

-

0.099(0.163)

-

Δ Hemoglobin (g/l)

−0.008(0.910)

-

−0.030(0.675)

-

0.081(0.256)

-

0.080 (0.134)

-

0.079(0.283)

-

ΔGlucose (mg/dl)

0.060(0.398)

-

−0.075(0.293)

-

−0.127(0.073)

-

−0.050 (0.705)

-

0.117(0.110)

-

ΔAverage 24-h SBP, mmHg

0.128(0.026)

0.249(0.001)

0.366(0.005)

0.268(0.017)

−0.429(<0.001)

−0.348(<0.001)

0.383(<0.001)

-

0.317(<0.001)

-

ΔAverage 24-h D BP, mmHg

−0.018(0.799)

-

−0.180(0.011)

-

0.079(0.263)

-

0.493(<0.001)

0.313(<0.001)

0.385(<0.001)

0.142(0.030)

ΔProteinuria (mg/day)

0.045(0.523)

-

−0.170(0.016)

-

0.060(0.400)

-

0.168(0.018)

0.133(0.018)

0.168(0.017)

0.131(0.028)

Δ CIMT(mm)

0.138(0.051)

-

−0.302(<0.001)

-

−0.065(0.364)

-

0.562(<0.001)

0.347(<0.001)

-

-

Δ Copeptin (ng/mL)

0.179(0.011)

0.267(<0.001)

0.599(<0.001)

0.582(<0.001)

−0.414(<0.001)

−0.331(<0.001)

-

-

0.562(<0.001)

0.391(<0.001)

ΔHs-CRP (mg/l)

0.120(0.034)

-

0.255(<0.001)

-

−0.182(0.009)

-

0.378(<0.001)

0.196(0.001)

0.372(<0.001)

0.210(0.001)