Variable | Area under curve | Diagnostic statistics | |||||
---|---|---|---|---|---|---|---|
AUC | p | Co-peptin cut-off used (from ROC) | SEN (%) | SPE (%) | PPV(%) | NPV(%) | |
FMD (> or ≤7.1%) | 0.75(0.68–0.80) | <0.001 | 0.59 ng/mL | 88.0(79.6–93.6) | 57.4(47.5–66.9) | 63.8(54.8–72.1) | 84.9(74.6–92.2) |
PWV (> or ≤7.8 m/sec) | 0.58(0.50–0.65) | 0.064 | 0.76 ng/mL | 51.1(40.4–61.7) | 71.3(61.8–79.6) | 60.8(48.5–71.2) | 63.1(53.9–71.7) |
eGFR(> or ≤59 mL/min/1.73 m2) | 0.61(0.54–0.68) | 0.008 | 0.81 ng/mL | 43.5(33.2–55.2) | 60.2(50.3–60.9) | 52.2(41.4–62.9) | 59.1(49.3–68.4) |
cIMT (> or ≤0.8 mm) | 0.86(0.80–0.90) | <0.001 | 0.58 ng/mL | 79.4(69.6–87.1) | 88.9(81.4–94.1) | 85.9(76.6–92.5) | 83.5(75.4–89.7) |