Table 6 Multivariate modeling to assess the independence of plasma copeptin as a marker of changes in cardiovascular function and eGFR
Variables | ΔFMD | ΔPWV | ΔeGFR | ΔcIMT | ||||
|---|---|---|---|---|---|---|---|---|
Univariate OR(95%CI) | Adjusted OR(95%CI) | Univariate OR(95%CI) | Adjusted OR(95%CI) | Univariate OR(95%CI) | Adjusted OR(95%CI) | Univariate OR(95%CI) | Adjusted OR(95%CI) | |
ΔLDL (mg/dl) | −0.109(0.125) | - | −0.179(0.011) | −0.162(0.018) | 0.007(0.925) | - | 0.072(0.311) | - |
ΔAverage 24-h SBP, (mmHg) | −0.167(0.018) | - | 0.015(0.828) | - | 0.112(0.115) | - | 0.017(0.810) | - |
ΔAverage 24-h D BP,(mmHg) | −0.061(0.394) | - | 0.007(0.917) | - | 0.104(0.142) | - | 0.055(0.442) | - |
ΔFMD (%) | - | - | −0.163(0.021) | - | 0.029(0.688) | - | −0.197(0.005) | - |
ΔPWV (m/sec) | −0.106(0.135) | - | - | - | 0.041(0.565) | - | −0.177(0.012) | −0.162(0.009) |
ΔeGFR(ml/min/1.73 m2) | −0.223(0.001) | −0.252(<0.001) | −0.265(<0.001) | −0.253(<0.001) | - | - | −0.448(<0.001) | −0.473(<0.001) |
ΔcIMT (mm) | −0.334(<0.001) | - | −0.024(0.737) | - | −0.188(0.008) | −0.188(0.008) | - | - |
ΔCopeptin (ng/mL) | −0.431(<0.001) | −0.448(<0.001) | 0.014(0.839) | - | −0.109(0.125) | - | −0.238(0.001) | −0.240(<0.001) |