Variables | eGFR (ml/min/1.73m2) | ||
---|---|---|---|
Reduced (< 60) n = 88,219 | Normal (≥ 60) n = 209,384 | p-value | |
Demographics | |||
Age | 77.7 ± 6.7 | 73.9 ± 6.3 | < 0.001 |
Gender | < 0.001 | ||
Female | 35,035 (39.7) | 109,225 (52.2) | |
Male | 53,184 (60.3) | 100,159 (47.8) | |
Marital status | < 0.001 | ||
Married/cohabiting | 62,820 (71.2) | 156,795 (74.9) | |
Widowed/divorced/separated | 19,878 (22.5) | 42,163 (20.1) | |
Never married | 4812 (5.5) | 9465 (4.5) | |
Missing value | 709 (0.8) | 961 (0.5) | |
BMI a | < 0.001 | ||
Underweight | 2762 (3.1) | 8722 (4.1) | |
Normal | 36,575 (41.5) | 100,671 (48.1) | |
Overweight | 29,309 (33.2) | 63,853 (30.5) | |
Obese | 18,568 (21.1) | 34,500 (16.5) | |
Missing value | 1005 (1.1) | 1638 (0.8) | |
Socioeconomic factors | |||
Educational attainment | < 0.001 | ||
With high school diploma or higher degree | 43,684 (49.5) | 104,614 (50.0) | |
Without high school diploma | 41,575 (47.1) | 99,686 (47.6) | |
Missing value | 2960 (3.4) | 5084 (2.4) | |
Income level | < 0.001 | ||
Not poor | 83,260 (94.4) | 201,548 (96.3) | |
Poor | 4959 (5.6) | 7836 (3.7) | |
Lifestyle factors | |||
Exercise habit | < 0.001 | ||
No | 12,212 (13.8) | 20,809 (9.9) | |
Occasional | 28,282 (32.1) | 64,843 (31.0) | |
Regular | 41,105 (46.6) | 106,449 (50.8) | |
Missing value | 6620 (7.5) | 17,283 (8.3) | |
Alcohol drinking | 0.1268 | ||
No | 86,177 (97.7) | 204,347 (97.6) | |
Yes | 1727 (2.0) | 4325 (2.1) | |
Missing value | 315 (0.3) | 712 (0.3) | |
Current smoking | < 0.001 | ||
No | 81,224 (92.1) | 195,386 (93.3) | |
Yes | 6709 (7.6) | 13,338 (6.4) | |
Missing value | 286 (0.3) | 660 (0.2) | |
Betel nut chewing | 0.0236 | ||
No | 87,470 (99.2) | 207,428 (99.1) | |
Yes | 270 (0.3) | 771 (0.4) | |
Missing value | 448 (0.5) | 1185 (0.5) | |
Blood and urine variables | |||
Fasting glucose | 106.9 ± 27.6 | 103.8 ± 22.9 | < 0.001 |
Total cholesterol | 191.9 ± 36.1 | 195.4 ± 34.8 | < 0.001 |
Triglyceride | 130.8 ± 77.9 | 116.5 ± 70.3 | < 0.001 |
HDL | 52.0 ± 14.6 | 55.7 ± 14.8 | < 0.001 |
Uric acid | 6.6 ± 1.7 | 5.6 ± 1.4 | < 0.001 |
BUN | 21.3 ± 7.7 | 16.0 ± 3.9 | < 0.001 |
Creatinine | 1.3 ± 0.5 | 0.9 ± 0.2 | < 0.001 |
Proteinuria | 13,758 (15.6) | 10,407 (5.0) | < 0.001 |
Comorbidity | |||
Hypertension | 47,553 (53.9) | 81,939 (39.1) | < 0.001 |
Diabetes | 19,802 (22.5) | 32,384 (15.5) | < 0.001 |
Dyslipidemia | 60,389 (68.5) | 136,984 (65.4) | < 0.001 |
Hyperuricemia/gout | 32,220 (36.5) | 26,981 (12.9) | < 0.001 |
Urinary tract stones | 1887 (2.1) | 4577 (2.2) | 0.4224 |
Cardiovascular disease | 24,101 (27.3) | 37,794 (18.1) | < 0.001 |
Cancer | 478 (0.5) | 1080 (0.5) | 0.3688 |