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Table 1 Characteristics of the study population

From: Protein energy-wasting associated with nephrotic syndrome – the comparison of metabolic pattern in severe nephrosis to different stages of chronic kidney disease

Variable

NS

n = 20

Control

n = 40

PreD

n = 40

HD

n = 20

p-value

History of NS:

Short (< 1 month)

n (%)

10 (50%)

Long (1–3 months)

n (%)

10 (50%)

    

Age [years]

mean ± SD

46 ± 17

48 ± 18

59 ± 15

49 ± 16

0.007

min-max

[22–79]

[19–86]

[19–83]

[19–78]

Body weight [kg]

mean ± SD

83 ± 14

86 ± 18

86 ± 15

79 ± 16

0.413

min-max

[60–105]

[53–126]

[53–115]

[56–106]

Height [cm]

mean ± SD

175 ± 10

176 ± 8

172 ± 7

175 ± 5

0.197

min-max

[155–187]

[158–194]

[154–192]

[167–185]

BMI [kg/m2]

mean ± SD

27.2 ± 3.5

27.6 ± 4.9

29.1 ± 4.8

25.9 ± 5.2

0.084

min-max

[21.5–35.0]

[18.1–38.1]

[19.3–38.3]

[18.1–35.8]

eGFR [mL/min/1.73m2]

mean ± SD

83 ± 29

86 ± 24

22 ± 4

8 ± 3

< 0.0001

min-max

[45–147]

[45–159]

[15–29]

[4–14]

Renal impairment:

No

n (%)

13 (65%)

32 (80%)

  

0.103#

Yes, CKD

n (%)

5 (25%)

8 (20%)

Yes, AKI

n (%)

2 (10%)

0

  

Serum creatinine [mg/dL]

median

1.1

1.0

3.1

7.4

< 0.0001*

(IQR)

(0.9–1.4)

(0.9–1.2)

(2.7–3.7)

(5.5–11.3)

min-max

[0.6–1.7]

[0.6–1.7]

[2.4–4.7]

[4.5–14.2]

C-reactive protein [mg/dL]

median

0.30

0.30

0.34

0.34

0.223*

(IQR)

(0.10–0.80)

(0.10–0.34)

(0.10–0.60)

(0.30–0.80)

min-max

[0.01–1.90]

[0.01–2.10]

[0.10–4.90]

[0.10–2.17]

  1. The average values were presented as mean ± SD or median (IQR), as appropriate. Four groups were compared with ANOVA or Kruskal-Wallis test (*) for continuous variables, and chi-square test for categorical data (#). Statistically significant differences between groups (p-values < 0.05) were bolded