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Table 5 Sensitivity, specificity, PPV and NPV of PLA2R and THSD7A

From: Diagnostic performance of glomerular PLA2R and THSD7A antibodies in biopsy confirmed primary membranous nephropathy in South Africans

 

Sensitivity

Specificity

PPV

NPV

PLA2R

51.2 (35.1–67.1)

100 (92.5–100)

100 (83.9–100)

96.7 (95.5–97.5)

THSD7A

4.9 (0.6–16.5)

100 (92.5–100)

100 (93.3–94.1)

93.7 (93.3–94.1)

PLA2R & THSD7A

53.7 (37.4–69.3)

100 (92.5–100)

100 (84.6–100)

71.2 (58.7–81.7)

  1. All values are presented as percentage and (95% confidence interval); PPV positive predictive value; NPV Negative predictive value; PLA2R phospholipase A-2 receptor; THSD7A thrombospondin type-1 domain containing 7A