Group and number of participants | FDI or Placebo n = 54 CKD, no anaemia but iron deficiency | FDI n = 26 | Placebo N = 28 |
---|---|---|---|
Age (years) (SD) | 59.6 (11.7) | 61.6 (10.1) | 57.8 (12.9) |
Range | 32–78 | 37–78 | 32–78 |
Sex | |||
Male | 26 (49%) | 11 (42.3%) | 15 (53.6%) |
Female | 27 (51%) | 14 (53.8%) | 13 (46.4%) |
Unknown | 1 | 1 | 0 |
Ethnicity | |||
White | 42 (78%) | 19 (73.1%) | 23 (82.1%) |
Asian | 3 (5%) | 1 (3.8%) | 2 (7.1%) |
Black | 7 (13%) | 4 (15.4%) | 3 (10.7%) |
Mixed Race | 1 (2%) | 1 (3.8%) | 0 (0%) |
Unknown/other | 1 (2%) | 1 (3.8%) | 0 (0%) |
Smoker | |||
Yes; current | 5 (9%) | 1 (3.8%) | 4 (14.3%) |
Yes; previous | 17 (32%) | 8 (30.8%) | 9 (32.1%) |
No | 32 (59%) | 17 (65.4%) | 15 (53.6%) |
Body Mass Index (BMI) | 30.3 (6.5), 53 | 30.7 (6.8) | 30.01 (6.4) |
Serum Ferritin (SF) (microg/L) | 66.3 (44.1) 53 | 64.2 (29.1) 26 | 68.4 (55.3) 27 |
Transferrin Saturation % (TSAT) | 20.1 (7.4) 53 | 22.3 (8.8) 26 | 19.7 (5.6) 27 |
Haemoglobin (Hb) (g/L) | 128.7 (10.1), 54 | 131 (7.4), 26 | 126.6 (11.8), 28 |
Serum Creatinine (micromol/L) | 186.7 (58.6), 54 | 167 (40.2), 26 | 204.9 (67.3), 28 |
eGFR (ml/min/1.73m2) | 31.1 (9.6), 54 | 33.2 (9.3), 26 | 29.1 (9.6), 28 |
Cystatin C | 2.2 (0.6), 52 | 2.1 (0.5), 26 | 2.4 (0.6), 26 |
uACR (mg/mmol) | 60.9 (133.3), 26 | 26.9 (40), 13 | 94.8 (181.4), 13 |
uPCR (mg/mmol) | 83.8 (128.4), 40 | 51.9 (59.3), 19 | 112.7 (164.8), 21 |
CRP (mg/L) | 5.0 (4.4), 53 | 6.3 (5.5), 26 | 3.8 (2.4), 27 |
Serum Albumin (g/L) | 39.8 (5.6) | 40.8 (4.2) | 38.8 (6.9) |
Platelet count (X105) | 235 (58.9) | 226 (52.4) | 243 (64.1) |
Phosphate (mmol/L) | 1.2 (0.2) | 1.1 (0.2) | 1.2 (0.2) |
NT pro BNP (ng/L) | 485.2 (1268.4), 51 | 422.5 (881.9), 25 | 545.4 (1569.5), 26 |
PWV measurement | 8.3 (3.2), 54 | 8.3 (2.8), 26 | 8.3 (3.6), 28 |
AiX measurement | 24.2 (10.7) 54 | 25.4 (10.7) 26 | 24.1 (10.8) 28 |
6MWT Metres (m) | 401.2 (120.2), 52 | 386.6 (135.8), 25 | 414.7 (104.5), 27 |
KD-KQoL SF36 (normalised data) | 40.2 (10.4), 48 | 40.2 (10.4), 21 | 40.4 (9.55), 27 |
MLHF | 23.97 (26.3) | 22.7 (25.7) 18 | 25.0 (27.3) 24 |
Systolic Blood Pressure (mmHG) | 133.6 (19.5), 54 | 138.2 (19.9), 26 | 129.4 (18.4), 28 |
Diastolic Blood Pressure (mmHG) | 77.3 (11.3), 54 | 78.5 (10.7), 26 | 76.2 (11.8), 28 |
Baseline ECG | |||
N | 38 | 17 | 21 |
NCS | 13 | 8 | 5 |
ACL | 1 | 1 | 0 |
Not Recorded | 2 | 0 | 2 |
Diabetes | 17 | 8 | 9 |
Hypertension | 4 | 2 | 2 |
Polycystic Kidney Disease | 5 | 2 | 3 |
Pyelonephritis/Reflux | 3 | 1 | 2 |
Glomerulonephritis / IgA/vasculitis/interstitial nephritis | 14 | 8 | 6 |
Other/unknown | 11 | 5 | 6 |