Effect of 0.9% NaCl compared to plasma-lyte on biomarkers of kidney injury, sodium excretion and tubular transport proteins in patients undergoing primary uncemented hip replacement – a randomized trial

Table 8 Electrolytes

Period	Baseline	After surgery	Post-operative day	P-value (difference in response)
p-Na (mmol/L)
PlasmaLyte	140 ± 2	140 ± 3	136 ± 3*	0.550
Sodiumchloride	139 ± 2	140 ± 2	135 ± 4*	0.550
p-K (mmol/L)
PlasmaLyte	3.9 ± 0.4	3.6 ± 0.3*	3.9 ± 0.4	0.346
Sodiumchloride	4.0 ± 0.3	3.8 ± 0.2 *	3.9 ± 0.2*	0.346
p-Albumin (g/L)
PlasmaLyte	40 ± 2	35 ± 2*	34 ± 2*	0.447
Sodiumchloride	39 ± 2	34 ± 2*	34 ± 2*	0.447
p-Creatinine (μmol/l)
PlasmaLyte	74 ± 14	66 ± 13*	66 ± 14*	0.264
Sodiumchloride	74 ± 10	68 ± 8*	65 ± 9*	0.264
p-Hgb (mmol/L)
PlasmaLyte	8.7 ± 0.6	7.9 ± 0.7*	7.4 ± 0.4*	0.931
Sodiumchloride	8.6 ± 0.6	7.8 ± 0.5*	7.4 ± 0.8*	0.931

Plasma concentrations of sodium (p-Na), potassium (p-K), albumin (p-Albumin), creatinine (p-creatinine) and Hemoglobin (p-Hgb). Values are shown as means ± SD or medians with 25 and 75 percentiles in brackets. P-value represents probability of difference in response (response from baseline to infusion) between treatments. Paired t-test or Wilcoxon signed rank test was used to test statistical significant difference from baseline, * = p < 0.05

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