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Table 1 Baseline demographics, overall and per treatment arm

From: A randomised controlled trial to examine the effects of cinacalcet on bone and cardiovascular parameters in haemodialysis patients with advanced secondary hyperparathyroidism

 

All patients (n = 36) Mean (SD) / Median [range]/ n (%)

Cinacalcet (n = 15) Mean (SD) / Median [range] / n (%)

Control (n = 21) Mean (SD) / Median [range]/ n (%)

p-Value

Demographics

 Age

51 (15)

45 (16)

54 (13)

0.068

 Male

23 (64%)

11 (73%)

12 (57%)

0.319

 Caucasian

30 (83%)

14 (93%)

16 (76%)

0.174

 Diabetes

4 (11%)

1 (7%)

3 (14%)

0.473

 Smoking

9 (25%)

5 (33%)

4 (19%)

0.329

 Height (cm)

166 (11)

169 (11)

163 (11)

0.298

 Weight (kg)

73 (15)

74 (15)

72 (15)

0.626

 BMI

26 (5)

25 (5)

26 (5)

0.927

Cardiovascular

 SBP (mmHg)

131 (26)

133 (27)

130 (26)

0.789

 DBP (mmHg)

72 (13)

72 (13)

72 (13)

0.877

 MI

5 (14%)

2 (13%)

3 (14%)

0.935

 Angina

7 (19%)

5 (33%)

2 (10%)

0.075

 Stroke

3 (8%)

0

3 (14%)

0.126

 TIA

7 (19%)

2 (13%)

5 (24%)

0.433

 All CVD

14 (39%)

6 (40%)

8 (38%)

0.908

 NYHA score

1: 26 (72%)

1: 10 (67%)

1: 16 (76%)

0.529

2–3:10 (28%)

2–3:5 (33%)

2–3:5 (24%)

 

 CCS score

0:33 (92%)

0: 14 (93%)

0: 19 (91%)

0.759

1–3: 3 (8%)

1–3: 1 (7%)

1–3: 2 (9%)

 

Renal history

 Adequate dialysis

23 (80%)

8 (73%)

15 (83%)

0.265

 Dialysis duration (m)

38 [6–319]

33 [6–319]

43 [10–222]

0.072

 Previous transplant

9 (25%)

4 (27%)

5 (24%)

0.845

Hyperparathyroidism medication at baseline

 Calcium binder

15 (42%)

7 (47%)

8 (38%)

0.607

 Non-calcium binder

30 (83%)

13 (87%)

17 (81%)

0.650

 VDRA

35 (97%)

15 (100%)

20 (95%)

1.000

  1. MI myocardial infarction, TIA transient ischaemic attack, CVD cardiovascular disease, NYHA New York Heart Association heart failure score, CCA Canadian Cardiovascular Society angina score, VDRA vitamin D receptor analogue, iPTH intact parathyroid hormone, CRP C-reactive protein, SBP systolic blood pressure, DBP diastolic blood pressure, BMI Body mass index