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Table 3 Baseline demographics of the recruited haemodialysis patients

From: Investigating the utility of COVID-19 antibody testing in end-stage renal disease patients receiving haemodialysis: a cohort study in the United Kingdom

Variable

Total patients

(269)

COVID-19 rRT-PCR positive (32)

COVID-19 rRT-PCR

negative (237)

p-value

positive vs negative

Age, years

61 (50–73)

62 (54–75)

60 (50–73)

0.663

Gender, male

177 (65.7%)

22 (68.7%)

150 (63.3%)

0.546

Ethnicity, Caucasian

196 (72.8%)

25 (78%)

171 (72.2%)

0.476

BAME

73 (27.2%)

7 (22%)

66 (27.8%)

 

Smoking history

32 (11.9%)

8 (25%)

24 (10.1%)

0.344

Weight, Kg

76 (64–89.5)

81.5 (63–95)

75 (65–89)

0.405

BMI, Kg/m2

27 (23–31)

26.5 (22.5–32)

27 (24–31)

0.939

Diabetes mellitus

97 (36.1%)

9 (28.1%)

88 (37.1%)

0.319

CVD

60 (22.3%)

8 (25%)

52 (21.9%)

0.696

RASi

93 (34.6%)

9 (28.1%)

84 (35.4%)

0.414

Frail (CFS>/=5), n = 189

73/189 (38.6%)

18/28 (64.3%)

55/161 (34.1%)

0.003

Dialysis vintage, months

26 (11–64)

42 (14–71)

25 (10–61)

0.658

Dialysis access, AVF

167 (62.1%)

21 (65.5%)

146 (61.6%)

0.701

URR, %

72 (65–78)

69 (66–77)

73 (67–78)

0.162

Albumin, g/L, n = 262

37 (34–40)

38 (34–40)

37 (34–40)

0.873

Ferritin, ng/mL, n = 262

367 (208–652)

364 (239–706)

368 (208–647)

0.761

TSats, %, n = 262

24 (16–34)

27 (17–36)

24 (16–34)

0.418

Vitamin D level, nmol/L, n = 211

43 (28–55)

42 (24–53)

37 (30–71)

0.613

Haemoglobin, g/L, n = 214

107 (96–117)

103 (86–120)

107 (96–117)

0.616

WCC, ×109/L, n = 214

7 (5–8)

6.6 (4–9)

7 (5–8)

0.925

Lymphocytes, ×109/L,

n = 214

1.1 (0.7–1.45)

0.75 (0.5–1.2)

1.10 (0.8–1.5)

0.005

Platelet count, ×109/L, n = 214

204 (157–256)

189 (117–262)

207 (158–254)

0.286

Outcomes on follow-up

 Follow up, months

7.6 (6.9–8.1)

8.7 (8.1–8.9)

7.2 (6.8–8)

< 0.001

 COVID-19 associated hospital admission

28 (10.4%)

25 (78.1%)

3 (1.26%)

< 0.001

 ICU admission

3

3

0

–

 Deaths

18 (6.7%)

6 (18.7%)

12 (5.9%)

0.003

  1. Categorical variables are expressed as number (%), and the p-value was derived using the Chi-square test. Continuous variables are expressed as median (interquartile range) and the Mann-Whitney U test was used to calculate the p-value
  2. BAME black Asian minority ethnicity, BMI body mass index, CVD cardiovascular disease, RASi renin-angiotensin system inhibitors, CFS clinical frailty score, AVF arterio-venous fistula, URR urea reduction ratio, WCC white cell count, TStats transferrin saturations, ICU intensive care unit