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Table 2 Cox proportional hazard ratios of LDL-C < 1.8 mmol/L vs. LDL-C ≥ 1.8 mmol/L for long-term all-cause mortality in different models

From: Association between baseline LDL-C and prognosis among patients with coronary artery disease and advanced kidney disease

 

HR

95% CI

P Value

Univariate Cox model

1.53

1.18

1.99

0.001

Model 1

1.52

1.17

1.98

0.002

Model 2

1.47

1.13

1.91

0.004

Model 3

1.58

1.16

2.14

0.003

Model 4

1.40

1.08

1.83

0.012

Model 5

1.45

1.12

1.88

0.005

Model 6

1.38

1.01

1.89

0.042

  1. Model 1: Adjusted for age and male
  2. Model 2: Adjusted for nutritional status: albumin
  3. Model 3: Adjusted for lipid variables: total cholesterol, triglyceride, high-density lipoprotein cholesterol
  4. Model 4: Adjusted for variables associated with cardiovascular disease: ACS, CHF, hypertension, PAD, previous AMI, PCI, Lg ProBNP
  5. Model 5: Adjusted for variables associated with kidney disease: dialysis, 15 ≤ eGFR < 30 ml/min/1.73 m2 vs. eGFR < 15 ml/min/1.73 m2
  6. Model 6: Adjusted for full multivariate variables: age, male, current smoker, ACS, CHF, hypertension, diabetes mellitus, dialysis, anemia, PAD, 15 ≤ eGFR < 30 ml/min/1.73 m2 vs. eGFR < 15 ml/min/1.73 m2, previous AMI, PCI, WBC, albumin, total Cholesterol, triglyceride, high-density lipoprotein cholesterol, Lg ProBNP, Lg D-dimer, ACEI/ARB, β-blockers, statins, diuretics