Fig. 1

Renal biopsy histopathology. a Light microscopic findings indicate global sclerosis in half of the glomeruli. However, the other glomeruli showed minor lesions (periodic acid-silver methenamine stain; original magnification, 200×). b Moderate fibrosis was observed in the interstitial area, and moderate atrophy was observed in the tubules (periodic acid-silver methenamine stain; original magnification, 100×). Irregular splitting TBM was also observed in some tubules (arrowhead). c There were no significant findings in immunofluorescence analysis. d No electron dense deposits were detected by electron microscopy. e Cyst-like expansion of the tubular was unclear. Tubular atrophy was dominantly found in the distal tubule by CK7 staining (original magnification, 100×)