Variable | Phase 3 April 2006 | Phase 4 August 2009 | Phase 5 April 2013 | Phase 6 August 2017 |
---|---|---|---|---|
N | 1765 | 1633 | 1731 | 1753 |
Mean age, years | 62.5 (12.5) | 64.6 (12.1) | 65.2 (12.2) | 65.4 (11.8) |
Male, % | 60% | 62% | 65% | 67% |
Mean years on dialysis | 8.2 (7.1) | 8.3 (7.5) | 7.3 (7.6) | 7.1 (8) |
Mean sp Kt/V | 1.35 (0.27) | 1.40 (0.28) | 1.42 (0.28) | 1.49 (0.29) |
sp Kt/V ≥ 1.2, % | 71% | 77% | 79% | 85% |
Mean dialysis treatment duration, minutes | 238.2 (30.6) | 236.4 (28.4) | 238.4 (27.2) | 243.3 (26.7) |
Mean utrafiltration rate, mL/kg/hr | 11.3 (4.1) | 8.6 (3.5) | 8.7 (3.5) | 8.4 (3.3) |
Mean blood flow rate, mL/min | 198.3 (27) | 202.2 (27.5) | 207.9 (31.1) | 218.4 (35.3) |
Blood flow rate ≥ 200 mL/min, % | 65% | 72% | 78% | 85% |
Hemodiafiltration use, % | 6% | 6% | 8% | 23% |
Comorbidities, % | ||||
 Coronary heart disease | 41% | 33% | 24% | 25% |
  Congestive heart failure | 25% | 21% | 16% | 16% |
  Cerebrovascular disease | 13% | 15% | 11% | 17% |
  Other cardiovascular disease | 32% | 32% | 21% | 21% |
  Peripheral vascular disease | 17% | 20% | 13% | 12% |
  Hypertension | 73% | 79% | 80% | 85% |
  Diabetes | 32% | 35% | 40% | 43% |
  Gastrointestinal bleeding | 4% | 5% | 4% | 2% |
  Neurologic disease | 10% | 9% | 6% | 6% |
  Psychiatric disorder | 3% | 6% | 4% | 3% |
  Recurrent cellulitis | 4% | 5% | 3% | 3% |
  Cancer, non-skin | 9% | 11% | 10% | 12% |