Fig. 3

Key performance indicators (KPI) for each eGFR equation stratified by liver function (preserved vs. reduced). KPI evaluated were: median bias of eGFR to mGFR (A) and accuracy of eGFR measured as the percentage of samples with eGFR within 30% (P30) (B), 20% (P20) (C), and 15% (P15) (D) of mGFR. Error bars show the bootstrapped 95% confidence intervals (n = 1000). Solid lines of the error bars indicate the performance in the subgroup of patients with preserved liver function, while dashed lines indicate performance in patients with reduced liver function. Each eGFR equation is represented by a different color, whereas the tone of the color indicates the family of equations, with purple and pink encoding for creatinine-only equations [eGFRcr(ASR) and eGFRcr(AS)], dark and bright green encoding for creatinine and cystatin C-containing equations [eGFRcr-cys(ASR) and eGFRcr-cys(AS)], and blue encoding for the GFR_NMR equation