Table 1 Baseline characteristics of individuals stratified by quartiles of baseline serum ALB levels
Variable | ALL(n = 740) | ≤ 26.0 (n = 188) | 26.1–30.5 (n = 186) | 30.6–34.7 (n = 183) | ≥ 34.8 (n = 183) | P |
|---|---|---|---|---|---|---|
Age(years) | 71 (57, 82) | 73 (62, 83.5) | 73 (62.5, 83.5) | 75 (61.5, 83.5) | 69 (56, 81) | 0.006 |
Sex, Male(%) | 477 (64.5) | 125 (66.5) | 115 (61.8) | 119 (65) | 118(64.5) | 0.81 |
Comorbidities % (n) | ||||||
Diabetes | 174 (23.5) | 46 (24.5) | 39 (21.0) | 44 (24.0) | 45 (24.6) | 0.8 |
CHD | 137 (18.5) | 25 (13.3) | 30 (16.2) | 49 (26.8) | 33 (18.0) | 0.006 |
Hypertension | 375 (50.7) | 77 (41) | 94 (50.5) | 114 (62.3) | 90 (49.2) | 0.001 |
HF | 183 (24.7) | 43 (22.9) | 53 (28.5) | 48 (26.2) | 39 (21.3) | 0.37 |
CI | 131 (17.7) | 34 (18.1) | 31 (16.7) | 31 (16.9) | 35 (19.1) | 0.92 |
Cancer | 144 (19.5) | 37 (19.7) | 39 (21) | 29 (15.8) | 39 (21.3) | 0.53 |
COPD | ||||||
Sepsis | 283 (38.2) | 87 (46.3) | 89 (47.8) | 52 (28.4) | 55 (30.1) | < 0.001 |
CKD | 83 (11.2) | 21 (11.2) | 19 (10.2) | 19 (10.4) | 24 (13.1) | 0.80 |
Critical AKI | 585 (79.1) | 155 (82.4) | 145 (78) | 139 (76) | 146 (79.8) | 0.46 |
Medicine | ||||||
PPI | 571 (80.4) | 148 (83.6) | 149 (84.2) | 148 (83.1) | 126 (70.8) | 0.003 |
Diuretic | 502 (70.7) | 139 (78.5) | 125 (70.6) | 136 (76.4) | 102 (57.3) | < 0.001 |
ACEI | 19 (2.7) | 3 (1.7) | 3 (1.7) | 7 (3.9) | 6 (3.4) | 0.43 |
Albumin infusion | 60 (8.1) | 12 (6.4) | 15 (8.1) | 16 (8.7) | 17 (9.3) | 0.76 |
ARB | 87 (12.2) | 14 (7.9) | 15 (8.4) | 28 (15.7) | 30 (16.9) | 0.011 |
Laboratory data | ||||||
Scr (baseline) μmol/L | 88(71, 93.9) | 88 (71, 88) | 82.5 (71, 88) | 86.9 (71, 88.9) | 85.9 (71, 97) | 0.14 |
Neut × 109/L | 7.35(4.57, 11.79) | 8.4 (4.7, 12.6) | 9.0 (5.4, 13.3) | 8.3 (4.7, 12.2) | 5.8 (3.8, 9.7) | < 0.001 |
MCHC g/L | 329 (321, 338) | 327.0 (318.0, 337.0) | 329.0 (321.5, 338.0) | 326.0 (318.0, 336.5) | 330.0 (322.0, 338.0) | 0.009 |
WBC × 109/L | 9.14 (6.20, 13.75) | 9.57 (5.94, 14.32) | 10.45 (6.41, 14.9) | 9.82 (6.55, 14.54) | 7.92 (5.61, 11.80) | 0.004 |
RDW-SD fl | 45.3 (42.0, 50.3) | 46.5 (43.0, 51.0) | 45.2 (42.1, 50.2) | 45.5 (41.7, 50.75) | 44.9 (42.3, 49.1) | 0.062 |
BNP pg/ml | 301.2 (115.3, 983.5) | 308.8 (127.2, 994.4) | 377.7 (144.7, 977.2) | 402.0 (149.6, 1091.9) | 176.6 (66.2, 613.1) | 0.001 |
Glu mmol/L | 6.63 (5.12, 9.41) | 7.36 (5.28, 10.37) | 7.04 (5.09, 10.29) | 7.08 (5.21, 9.30) | 6.18 (5.12, 8.38) | 0.18 |
CRP mg/L | 46.55 (11.32, 115.7) | 97.6 (39.0, 221.6) | 74.4 (18.9, 147.1) | 45.6 (12.2, 97.1) | 12.6 (3.7, 40.2) | < 0.001 |
Hb g/L | 105 (86, 126) | 92 (75.5, 108.5) | 103.0 (85.0, 122.5) | 110.0 (90.0, 129.0) | 119.0 (96.0, 136.0) | < 0.001 |
Alb g/L | 30.4 ± 6.39 | 22.3 ± 2.90 | 28.5 ± 1.27 | 32.6 ± 1.23 | 38.3 ± 3.37 | < 0.001 |
TG | 1.24 (0.88, 1.80) | 1.22 (0.81, 1.68) | 1.19 (0.86, 1.77) | 1.16 (0.87, 1.70) | 1.15 (0.86, 1.79) | 0.73 |
TC | 3.28 (2.42, 4.15) | 2.23 (1.65, 3.22) | 3.10 (2.27, 4.00) | 3.42 (2.80, 4.03) | 3.92 (3.31, 4.75) | < 0.001 |
ICU patients % (n) | 431 (58.2) | 109 (58.0) | 122 (65.6) | 114 (62.3) | 86 (47) | 0.002 |
CRRT %(n) | 350 (47.3) | 84 (44.7) | 86 (42.6) | 99 (54.1) | 81 (44.3) | 0.19 |
HA-AKI % (n) | 211 (28.5) | 39 (20.7) | 53 (28.5) | 55 (30.1) | 64 (35) | 0.023 |
90-day mortality %(n) | 464 (62.7) | 130 (69.1) | 127 (68.3) | 116 (63.4) | 97 (49.7) | < 0.001 |
1- year mortality %(n) | 488 (65.9) | 136 (72.3) | 133 (71.5) | 124 (67.8) | 95 (51.9) | < 0.001 |