Fig. 4
From: Performance of synacthen test in chronic hemodialysis patients
Changes in serum cortisol concentration during HD without Synacthen (A) and estimated smooth effects for HD time on serum cortisol concentration (nmol/l) on log-scale from a multivariable linear additive mixed model (B). Abbreviation: HD – hemodialysis. The random intercept has accounted for multiple cortisol measurements during HD for each subject and HD time was modelled using restricted cubic splines