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Table 1 Clinical and demographic characteristics of study participants at study begin

From: Performance of synacthen test in chronic hemodialysis patients

 

Total (N = 28)

Median age in years at study begin (IQR)

70.50 (63.00, 75.50)

Gender (male)

20 (71.4%)

Caucasian

25 (89.3%)

Previous kidney transplantation

2 (7.1%)

Previous glucocorticoid treatment ≥ 2weeks (≥ 1year ago)

5 (17.9%)

Median HD vintage in months (IQR)

36.50 (15.50, 77.50)

Dialysis access: Arteriovenous fistula / graft

24 (85.7%)

Cause of end stage kidney disease (ESKD)

 

- Vascular

- Diabetes

- ADPKD

- Glomerulonephritis

- Tubulointerstitial disease

- Other*/ Unknown

11 (39.3%)

10 (35.7%)

1 (3.6%)

4 (14.3%)

1 (3.6%)

11 (39.3)

Patients with multiple causes of ESKD

7 (25%)

Native kidney biopsy

10 (35.7%)

Comorbidities

 

- Coronary artery disease

- Congestive heart failure

- Hypertension

- Peripheral artery occlusive disease

- Diabetes mellitus

- Obesity

- Neoplastic disease

- Other**

9 (32.1%)

7 (25.0%)

24 (85.7%)

14 (50.0%)

13 (46.4%)

6 (21.4%)

4 (14.3%)

7 (25.0%)

Patients with multiple comorbidities

25 (89.3%)

Concomitant medication

 

- Loop diuretics

- Thiazide diuretics

- RAAS inhibitor

- CCB blocker

- BB

- Insulin

17 (60.7%)

7 (25.0%)

10 (35.7%)

6 (21.4%)

18 (64.3%)

7 (25.0%)

  1. Abbreviations: ADPKD – autosomal-dominant polycystic kidney disease; BB – beta blocker; CCB – calcium channel antagonist; HD – HD; IQR – interquartile range; RAAS – renin-angiotensin-aldosterone system
  2. * Other ESKD: nephrectomy (bilateral or unilateral), cardiorenal syndrome, cardiogenic shock, chronic hydronephrosis, acute tubular necrosis due to septic shock, lithium-associated nephropathy, secondary focal segmental glomerulosclerosis, thrombotic microangiopathy due to atypical hemolytic-uremic syndrome (factor H deficiency)
  3. ** Other comorbidities: hypertensive heart disease, valvular heart disease, atrial fibrillation, chronic bronchitis, chronic autoimmune thyroiditis, osteoporosis, benign prostatic hyperplasia, polyarthritis, polyneuropathy, idiopathic Parkinson’s disease