Table 1 Characteristics of the included studies
From: Frailty and prognosis of patients with kidney transplantation: a meta-analysis
Study | Location | Design | Number of patients | Mean age (years) | Male (%) | Timing of frailty assessment | Tools for the diagnosis of frailty | Number of patients with frailty | Follow-up duration | Outcomes reported | Variables adjusted |
|---|---|---|---|---|---|---|---|---|---|---|---|
Garonzik 2012 | USA | PC | 183 | 53 | 63.7 | Immediately prior to surgery | PFP | 46 | Within hospitalization | DGF | Age, BMI, ethnicity, DM, donor type, CIT, and preemptive KT |
McAdams 2015 | USA | PC | 537 | 53.2 | 60 | At admission for KT | PFP | 107 | 2.7 years | Mortality | Age, sex, ethnicity, DM, time on dialysis and preemptive KT, donor type, and CIT |
McAdams 2017 | USA | PC | 589 | NR | NR | At admission for KT | PFP | 141 | Within hospitalization | LOS | Age, sex, ethnicity, DM, BMI, year on dialysis, donor type and characteristics, and CIT |
Nastasi 2018 | USA | PC | 719 | 51.6 | 62.3 | At admission for KT | SPPB | 336 | 5 years | Mortality | Age, sex, ethnicity, BMI, years on dialysis, cause of ESRD, donor type, CVD, lung disease, and DM |
Konel 2018 | USA | PC | 773 | 54 | 62.2 | At admission for KT | PFP | 126 | 5 years | Mortality | Age, sex, ethnicity, education, BMI, cause of ESRD, time on dialysis, modified CCI, and donor type. |
Schaenman 2019 | USA | RC | 60 | 52.2 | 65.2 | At admission for KT | FRS | 17 | Within hospitalization | LOS | Age |
Schopmeyer 2019 | The Netherlands | PC | 150 | 51.8 | 62.6 | At admission for KT | GFI | 23 | 30 days | POC | Age, CCI, smoking, duration of dialysis, type of transplantation, and re-transplantation |
Chu 2019 | USA | PC | 569 | 51.7 | 60.8 | At admission for KT | PFP | 91 | 4 years | LOS and mortality | Age, sex, ethnicity, BMI, DM, year on dialysis, cause of ESRD, donor type, and DGF |
Mantovani 2020 | Brazil | PC | 87 | 44.8 | 53.1 | At admission for KT | PFP | 32 | Within hospitalization | POC | Age, sex, ethnicity, cause of ESRD, BMI, CVD, DM, year of dialysis, and donor type |
Haugen 2021 | USA | PC | 378 | 53 | 65.9 | At admission for KT | IFI | 152 | 5 years | Mortality | Age, sex, ethnicity, donor type, CCI, cause of ESRD, and smoking status |
Chen 2021 | USA | PC | 1113 | 52.9 | 60.4 | At admission for KT | nPFP | 190 | 6.3 | Mortality | Age, sex, ethnicity, donor type and CCI |
Jose 2022 | Spain | RC | 296 | 62.6 | 70.6 | At admission for KT | PFP | 79 | 1.9 | Mortality | Age, sex, HTN, DM, CAD, HF, PAD, year of dialysis, SCr at 1 year |
Parajuli 2022 | USA | PC | 825 | 55.3 | 60 | At admission for KT | PFP | 95 | 2.8 | DGF and mortality | Age, sex, ethnicity, cause of ESRD (DM vs. other), previous transplant, living donor, depleting induction, pre-transplant dialysis duration |