Variable | level | Training cohort | Validation cohort | P value |
---|---|---|---|---|
674 | 289 | |||
Gender (%) | M | 402 (59.6) | 165 (57.1) | 0.51 |
F | 272 (40.4) | 124 (42.9) | ||
Age (years) (%) | < 65 | 434 (64.4) | 170 (58.8) | 0.12 |
>=65 | 240 (35.6) | 119 (41.2) | ||
Weight (kg) | 83.33 [71.15, 100.84] | 80.10 [70.00, 98.50] | 0.09 | |
Antibiotic (%) | no | 192 (28.5) | 88 (30.5) | 0.60 |
yes | 482 (71.5) | 201 (69.5) | ||
Hypertension (%) | no | 558 (82.8) | 249 (86.2) | 0.23 |
yes | 116 (17.2) | 40 (13.8) | ||
Alcohol abuse(%) | no | 485 (72.0) | 216 (74.7) | 0.42 |
yes | 189 (28.0) | 73 (25.3) | ||
Calculus gallbladder(%) | no | 524 (77.7) | 227 (78.6) | 0.85 |
yes | 150 (22.3) | 62 (21.4) | ||
PE (%) | no | 625 (92.7) | 268 (92.7) | 1 |
yes | 49 (7.3) | 21 (7.3) | ||
Sepsis (%) | no | 233 (34.6) | 109 (37.7) | 0.39 |
yes | 441 (65.4) | 180 (62.3) | ||
MI (%) | no | 605 (89.8) | 263 (91.0) | 0.64 |
yes | 69 (10.2) | 26 (9.0) | ||
CHF (%) | no | 549 (81.5) | 231 (79.9) | 0.64 |
yes | 125 (18.5) | 58 (20.1) | ||
CVD (%) | no | 632 (93.8) | 266 (92.0) | 0.40 |
yes | 42 (6.2) | 23 (8.0) | ||
CPD (%) | no | 528 (78.3) | 217 (75.1) | 0.31 |
yes | 146 (21.7) | 72 (25.9) | ||
Diabetes (%) | no | 450 (66.8) | 197 (68.2) | 0.73 |
yes | 224 (33.2) | 92 (31.8) | ||
Renal disease (%) | no | 566 (84.0) | 233 (80.6) | 0.24 |
yes | 108 (16.0) | 56 (19.4) | ||
Severe liver disease (%) | no | 591 (87.7) | 257 (89.9) | 0.66 |
yes | 83 (12.3) | 32 (11.1) | ||
CCI | 4.00 [2.00, 6.00] | 4.00 [2.00, 7.00] | 0.73 | |
SOFA | 4.00 [2.00, 7.00] | 4.00 [2.00, 6.00] | 0.82 | |
GCS | 15.00 [14.00, 15.00] | 15.00 [14.00, 15.000] | 0.31 | |
SIRS | 3.00 [2.00, 4.00] | 3.00 [3.00, 4.00] | 0.45 | |
HR max (beats/min) | 111.00 [94.25, 127.00] | 110.00 [93.00, 125.00] | 0.44 | |
HR min (beats/min) | 90.00 [75.00, 106.00] | 89.00 [76.00, 103.00] | 0.50 | |
MBP max (mmHg) | 96.00 [86.00, 111.00] | 96.00 [84.00, 109.00] | 0.31 | |
MBP min (mmHg) | 68.00 [57.00, 79.000] | 68.00 [57.00, 82.00] | 0.53 | |
RR max (breaths/min) | 27.00 [23.00, 32.000] | 27.00 [22.50, 32.00] | 0.89 | |
RR min (breaths/min) | 16.00 [13.13, 19.00] | 16.00 [13.50, 19.00] | 0.33 | |
TEM max (℃) | 37.06 [36.72, 37.56] | 37.06 [36.72, 37.56] | 0.75 | |
TEM min (℃) | 36.72 [36.44, 37.11] | 36.72 [36.39, 37.11] | 0.95 | |
Lactate (mmol/L) | 1.70 [1.30, 2.80] | 1.70 [1.20, 2.80] | 0.50 | |
PH | 7.37 [7.29, 7.43] | 7.37 [7.30, 7.42] | 0.62 | |
PO2 (mmHg) | 82.00 [52.00, 127.00] | 82.00 [50.00, 138.00] | 0.91 | |
PCO2 (mmHg) | 39.00 [33.00, 46.00] | 39.00 [33.00, 46.00] | 0.87 | |
Hb min (g/dL) | 10.60 [8.90, 12.20] | 10.30 [8.60, 12.20] | 0.26 | |
MCV max (fl.) | 93.00 [88.00, 98.00] | 94.00 [89.00, 99.00] | 0.15 | |
PLT min(×109/L) | 200.00 [133.25, 287.75] | 185.00 [130.00, 282.00] | 0.25 | |
WBC max(×109/L) | 13.80 [9.70, 19.60] | 12.900 [9.20, 19.10] | 0.36 | |
MCH max (pg) | 30.45 [28.93, 32.10] | 30.90 [29.20, 33.10] | 0.02 | |
MCHC max (g/L) | 33.03 (1.68) | 33.19 (1.87) | 0.19 | |
RBC max (×1012/L) | 3.66 [3.13, 4.28] | 3.55 [3.06, 4.15] | 0.08 | |
RDW max | 15.00 [13.90, 16.58] | 15.00 [13.80, 16.80] | 0.60 | |
HCT | 34.30 [29.50, 39.48] | 33.60 [29.50, 38.20] | 0.32 | |
Aniongap | 15.00 [13.00, 18.46] | 15.00 [12.50, 18.50] | 0.14 | |
Bicarbonate (mmol/L) | 22.00 [18.00, 25.00] | 22.00 [19.00, 25.00] | 0.59 | |
BUN max (mg/dL) | 23.00 [13.00, 39.00] | 21.00 [13.00, 35.00] | 0.56 | |
Ca max (mg/dL) | 8.20 [7.60, 8.80] | 8.10 [7.60, 8.80] | 0.53 | |
Glucose max (mg/dL) | 140.00 [110.00, 195.50] | 138.00 [109.00, 198.00] | 0.83 | |
Na max (mmol/L) | 139.00 [136.00, 142.00] | 138.00 [135.00, 142.00] | 0.04 | |
K max (mmol/L) | 4.20 [3.80, 4.70] | 4.30 [3.80, 4.70] | 0.54 | |
Cl max (mmol/L) | 105.00 [100.00, 110.00] | 104.00 [100.00, 109.00] | 0.31 | |
Cr max (mg/dL) | 1.10 [0.70, 1.90] | 1.00 [0.70, 1.70] | 0.42 | |
Alb (g/dL) | 2.80 [2.30, 3.30] | 2.80 [2.40, 3.20] | 0.67 | |
INR max | 1.30 [1.20, 1.60] | 1.30 [1.20, 1.60] | 0.79 | |
PT max (s) | 14.50 [13.20, 17.40] | 14.40 [13.10, 17.90] | 0.61 | |
ALT max (U/L) | 48.00 [24.00, 117.75] | 41.00 [22.00, 106.00] | 0.30 | |
ALP max (U/L) | 110.00 [71.00, 198.00] | 109.00 [69.00, 190.00] | 0.85 | |
AST max (U/L) | 71.00 [34.00, 188.00] | 58.00 [31.00, 125.00] | 0.02 | |
Tbil max (mg/dL) | 1.00 [0.60, 2.70] | 0.90 [0.50, 3.00] | 0.84 | |
Ventilation (%) | no | 619 (91.8) | 269 (93.1) | 0.60 |
yes | 55 (8.2) | 20 (6.9) | ||
Vasopressin (%) | no | 476 (70.6) | 211 (73.0) | 0.50 |
yes | 198 (29.4) | 78 (27.0) | ||
Fluid Intake (ml/kg/d) (%) | < 50 | 262 (38.9) | 136 (47.1) | 0.02 |
>=50 | 412 (61.1) | 153 (52.9) | ||
UO (ml/kg/h) (%) | < 0.5 | 216(32.0) | 82 (28.4) | 0.29 |
>=0.5 | 458 (68.0) | 207 (71.6) | ||
Los hospital (days) | 16.79 [7.94, 30.14] | 13.09 [7.50, 23.76] | 0.01 | |
Los ICU (days) | 3.58 [1.94, 9.25] | 3.21 [1.86, 7.00] | 0.12 | |
AKI (%) | no | 183 (27.2) | 85 (29.4) | 0.52 |
yes | 491 (72.8) | 204 (70.6) |