Table 1 Baseline characteristics
Parameters | Total population with CKD | CKD only | CKD + T2D | CKD + HF | CKD + T2D + HF |
|---|---|---|---|---|---|
N = 112,050 | N = 77,321 | N = 22,345 | N = 8,654 | N = 3,317 | |
Gender | |||||
Male | 48,130 (43) | 31,133 (40) | 11,323 (51) | 3,760 (43) | 1,710 (52) |
Female | 63,920 (57) | 46,188 (60) | 11,022 (49) | 4,894 (57) | 1,607 (48) |
Age (years), mean (SD) | 72 (12) | 72 (12) | 71 (11) | 81 (10) | 77 (10) |
CKD stage | |||||
1 | 5,097 (5) | 2,722 (4) | 2,176 (10) | 83 (1) | 93 (3) |
2 | 1,150 (1) | 707 (1) | 334 (1) | 58 (1) | 46 (1) |
3a | 23,826 (21) | 16,671 (22) | 4,279 (19) | 2,001 (23) | 837 (25) |
3b | 8,145 (7) | 4,537 (6) | 1,557 (7) | 1,431 (17) | 589 (18) |
4 | 1,920 (2) | 897 (1) | 321 (1) | 475 (5) | 208 (6) |
5 | 313 (< 0.5) | 169 (< 0.5) | 53 (< 0.5) | 46 (1) | 34 (1) |
Not specified | 71,599 (64) | 51,618 (67) | 13,625 (61) | 4,560 (53) | 1,510 (46) |
KDIGO risk categories [10] | |||||
Moderate risk | 27,766 (25) | 18,184 (24) | 7,210 (32) | 1,482 (17) | 842 (25) |
High risk | 8,626 (8) | 4,908 (6) | 2,325 (10) | 841 (10) | 536 (16) |
Very high-risk | 5,079 (5) | 2,359 (3) | 1,280 (6) | 878 (10) | 534 (16) |
Not specified | 70,579 (63) | 51,870 (67) | 11,530 (52) | 5,453 (63) | 1,405 (42) |
Comorbidities | |||||
Cardiovascular disease | 71,046 (63) | 45,983 (59) | 12,785 (57) | 8,654 (100) | 3,317 (100) |
Ischemic heart disease | 25,499 (23) | 14,103 (18) | 5,516 (25) | 3,948 (46) | 1,795 (54) |
Heart failure | 12,048 (11) | 0 | 0 | 8,654 (100) | 3,317 (100) |
Atrial fibrillation | 16,332 (15) | 8,719 (11) | 2,497 (11) | 3,737 (43) | 1,326 (40) |
Cerebrovascular event | 17,827 (16) | 11,594 (15) | 3,213 (14) | 2,169 (25) | 776 (23) |
Peripheral artery disease | 24,361 (22) | 16,887 (22) | 3,088 (14) | 3,392 (39) | 909 (27) |
Diabetes mellitus | |||||
Type 1 diabetes mellitus | 413 (< 0.5%) | ||||
Type 2 diabetes mellitus | 25,662 (23%) | ||||
Cancer | 17,010 (15) | 11,646 (15) | 3,172 (14) | 1,529 (18) | 608 (18) |
COPD | 13,265 (12) | 7,788 (10) | 2,413 (11) | 2,120 (24) | 906 (27) |
Medication | |||||
ACE inhibitors | 33,531 (30) | 20,345 (26) | 8,532 (38) | 3,038 (35) | 1,467 (44) |
Angiotensin 2 inhibitors | 29,039 (26) | 18,783 (24) | 6,759 (30) | 2,306 (27) | 1,054 (32) |
Statins | 57,979 (52) | 34,631 (45) | 16,554 (74) | 4,142 (48) | 2,397 (72) |
Clinical/laboratory parameters | |||||
UACR | |||||
<3 mg/mmol | 49,139 (44) | 33,977 (44) | 10,938 (49) | 2,808 (32) | 1,349 (41) |
3–30 mg/mmol | 22,794 (20) | 13,692 (18) | 6,618 (30) | 1,452 (17) | 971 (29) |
>30 mg/mmol | 2,868 (3) | 1,393 (2) | 1,010 (5) | 213 (2) | 234 (7) |
Unknown | 37,249 (33) | 28,259 (37) | 3,779 (17) | 4,181 (48) | 763 (23) |
Systolic blood pressure (mmHg), mean (SD) | 138 (17) | 138 (17) | 138 (16) | 135 (19) | 135 (19) |